Tripleipso-defluoroetherification of (trifluoromethyl)alkenes with fluoroalkylated alcohols: access to fluoroalkylated orthoestersviaC(sp3)

Tripleipso-defluoroetherification of (trifluoromethyl)alkenes with fluoroalkylated alcohols: access to fluoroalkylated orthoestersviaC(sp³)–F bond cleavage

Published:2023 Issue:53 Volume:59 Page:8238-8241
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Nie Jia¹,Jiang Huanfeng¹^ORCID,Zhu Chuanle¹²^ORCID

Affiliation:

1. Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China

2. Pazhou Lab, Guangzhou, 510330, China

Abstract

Tripleipso-defluoroetherification of (trifluoromethyl)alkenes with fluoroalkylated alcohols to synthesize fluoroalkylated orthoesters by C(sp3)–F bond cleavage.

Funder

National Natural Science Foundation of China

Basic and Applied Basic Research Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC01760E

Reference77 articles.

1. C−F Bond Activation in Organic Synthesis

2. Review of recent advances in CF bond activation of aliphatic fluorides

3. Activation of C–F bonds α to C–C multiple bonds

4. Synthesis and Metal-Catalyzed Reactions of gem-Dihalovinyl Systems

5. Functionalization of Fluorinated Molecules by Transition-Metal-Mediated C–F Bond Activation To Access Fluorinated Building Blocks

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