Transfection-capable polycationic nanovectors which include PEGylated-cyclodextrin structural units: a new synthesis pathway

Author:

Dascalu A. I.1234,Ardeleanu R.1234,Neamtu A.12345,Maier S. S.12346,Uritu C. M.1234,Nicolescu A.1234,Silion M.1234,Peptanariu D.1234,Calin M.784,Pinteala M.1234ORCID

Affiliation:

1. Centre of Advanced Research in Bionanoconjugates and Biopolymers

2. “Petru Poni” Institute of Macromolecular Chemistry

3. 700487 Iasi

4. Romania

5. Regional Institute of Oncology (IRO)

6. “Gheorghe Asachi” Technical University of Iasi

7. “Nicolae Simionescu” Institute of Cellular Biology and Pathology

8. Bucharest

Abstract

Polycationic nanoentities with low variability are able to act as cooperating carriers for dsDNA complexation and transport.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Reference62 articles.

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2. Gene delivery to carcinoma cells via novel non-viral vectors: Nanoparticle tracking analysis and suicide gene therapy

3. B. Alberts , A.Johnson, J.Lewis, M.Raff, K.Roberts and P.Walter, in Biology of the Cell, ed. J. H. Wilson and T. Hunt, Garland Science, New York, 4th edn, 2002, ch. 4, pp. 191–234

4. Design and application of multifunctional DNA nanocarriers for therapeutic delivery

5. From rationally designed polymeric and peptidic systems to sophisticated gene delivery nano-vectors

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