Novel biotin-linked amphiphilic calix[4]arene-based supramolecular micelles as doxorubicin carriers for boosted anticancer activity-Reference-Cited by-同舟云学术

Novel biotin-linked amphiphilic calix[4]arene-based supramolecular micelles as doxorubicin carriers for boosted anticancer activity

Published:2023 Issue:83 Volume:59 Page:12487-12490
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Du Dan¹²,Liu Yu-dun¹²,Lan Jun-bing¹²,Hou Xue-li¹²,Liu Jia-dong¹²,Shi Qing-hua¹²,Huang Qing-wen¹²,Xue Yun-sheng¹²,Yan Chao-Guo³^ORCID,An Lin¹²^ORCID

Affiliation:

1. College of Pharmacy, Xuzhou Medical University, Xuzhou 221004, P. R. China

2. New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, P. R. China

3. College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, P. R. China

Abstract

The lack of targeting, severe toxicity on normal tissues have become an intractable limitation of doxorubicin (DOX)-based chemotherapy. A biotin-modified calix[4]arene based therapeutic agent BPCA4 has been designed for the delivery of DOX to alleviate the adverse side effects.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC04102F

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