Design, characterization and pharmaceutical/pharmacological applications of ibuprofen conjugates based on hydroxyethylcellulose-Reference-Cited by-同舟云学术

Design, characterization and pharmaceutical/pharmacological applications of ibuprofen conjugates based on hydroxyethylcellulose

Published:2017 Issue:80 Volume:7 Page:50672-50679
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Abbas Khawar¹²³⁴,Amin Muhammad¹²³⁴,Hussain Muhammad Ajaz¹²³⁴^ORCID,Sher Muhammad¹²³⁴,Abbas Bukhari Syed Nasir⁵⁶⁷⁸⁹^ORCID,Edgar Kevin J.¹⁰¹¹¹²¹³¹⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Sargodha

3. Sargodha 40100

4. Pakistan

5. Department of Pharmaceutical Chemistry

6. College of Pharmacy

7. Aljouf University

8. Sakaka 2014

9. Saudi Arabia

10. Department of Sustainable Biomaterials

11. Macromolecules Innovation Institute

12. Virginia Tech

13. Blacksburg

14. USA

Abstract

We synthesized polymeric prodrugs of ibuprofen (IBU) based on hydroxyethylcellulose (HEC) which offered extended release and enhanced bioavailability of IBU as well as significant immunomodulatory potential in cytokine release assay.

Funder

Higher Education Commission, Pakistan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA08502H

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