Modular and divergent synthesis of 2,<i>N</i>3-disubstituted 4-quinazolinones facilitated by regioselective <i>N</i>-alkylation-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Modular and divergent synthesis of 2,N3-disubstituted 4-quinazolinones facilitated by regioselective N-alkylation

Published:2024 Issue:24 Volume:22 Page:4940-4949
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kim Kelly E.¹^ORCID,Comber Jason R.¹^ORCID,Pursel Alexander J.¹^ORCID,Hobby Grant C.¹,McCormick Carter J.¹^ORCID,Fisher Matthew F.¹,Marasa Kyle¹^ORCID,Perry Benjamin²

Affiliation:

1. Sciences and Mathematics Division, School of Interdisciplinary Arts and Sciences, University of Washington, Tacoma, WA 98402, USA

2. Drugs for Neglected Diseases initiative, Chemin Camille-Vidart 15, 1202 Geneva, Switzerland

Abstract

Synthesis of fifteen 2,N3-disubstituted 4-quinazolinones is achieved in three steps from simple building blocks, facilitated by a regioselective N-alkylation and application of principles from both modular and divergent synthesis.

Funder

Office of Research Central, University of Washington

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00564C

Reference47 articles.

1. Natural Products as Sources of New Drugs over the Last 25 Years

2. Natural products to drugs: natural product-derived compounds in clinical trials

3. On the potential of natural products in the discovery of pharma leads: A case for reassessment

4. Chemical genetics resulting from a passion for synthetic organic chemistry

5. PERSPECTIVE

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP