Synthesis and anti-infective potency study of a Ru-based complex bearing benzonitrile against <i>Staphylococcus aureus</i>-Reference-Cited by-同舟云学术

Synthesis and anti-infective potency study of a Ru-based complex bearing benzonitrile against Staphylococcus aureus

Published:2023 Issue:48 Volume:47 Page:22388-22401
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Huang Ziying¹,Jiang Guijuan¹,Song Yun¹,Chen Jingjing¹,Lin Wenjing¹,Yu Guangying¹,Duan Xuemin¹^ORCID,Xiong Yanshi¹,Wang Jintao¹^ORCID,Liao Xiangwen¹^ORCID,Liu Lianghong²

Affiliation:

1. Jiangxi Provincial Key Laboratory of Drug Design and Evaluation, School of Pharmacy, Jiangxi Science & Technology Normal University, Nanchang, 330013, China

2. School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, 418000, China

Abstract

A Ru-based antimicrobial agent (RuBZ) containing benzonitrile was prepared that exhibits robust potency against S. aureus in vitro, as well as low toxicity and high efficacy in vivo.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D3NJ04704K

Reference55 articles.

1. Emerging 2D MXenes for antibacterial applications: Current status, challenges, and prospects

2. Chimeric natural products derived from medermycin and the nature-inspired construction of their polycyclic skeletons

3. Antibiotic Discovery: Where Have We Come from, Where Do We Go?

4. Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance

5. Staphylococcus aureus: A Well–Armed Pathogen

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