Are highly morphed peptide frameworks lurking silently in microbial genomes valuable as next generation antibiotic scaffolds?
Author:
Affiliation:
1. ChEM-H Center
2. Stanford University
3. Stanford
4. USA
Abstract
Antibiotics are a therapeutic class that, once deployed, select for resistant bacterial pathogens and so shorten their useful life cycles.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/NP/C7NP00011A
Reference42 articles.
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4. The antibiotic resistome: the nexus of chemical and genetic diversity
5. A chemocentric view of the natural product inventory
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