A general approach to 2,2-disubstituted indoxyls: total synthesis of brevianamide A and trigonoliimine C

Author:

Xu Fan1ORCID,Smith Myles W.1ORCID

Affiliation:

1. Department of Biochemistry, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390, USA

Abstract

A general, user-friendly approach to 2,2-disubstituted indoxyls is presented. The method is particularly useful for the preparation of 2,2-dialkylindoxyl products, and is applied to concise total syntheses of brevianamide A and trigonoliimine C.

Funder

Welch Foundation

University of Texas Southwestern Medical Center

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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