Kinetic study of the alkaline degradation of imidapril hydrochloride using a validated stability indicating HPLC method

Author:

Abdulla Shabaan A.123,Frag Eman Y.45673,Ahmed Heba E.123

Affiliation:

1. National Organization for Drug Control and Research (NODCAR)

2. Cairo

3. Egypt

4. Chemistry Department

5. Faculty of Science

6. Cairo University

7. 12613 Giza

Abstract

An aqueous alkaline degradation study was performed for imidapril hydrochloride (IMD) drug in the presence of its degradation products and an isocratic stability indicating method was presented using HPLC.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference20 articles.

1. S. Budavari , The Merck Index Encyclopedia of Chemicals, Drugs and Biologics, Merck Research Laboratories, USA, 14th edn, 2006

2. Determination of a novel ACE inhibitor in the presence of alkaline and oxidative degradation products using smart spectrophotometric and chemometric methods

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