Stereoselective tandem iridium-catalyzed alkene isomerization-cope rearrangement of ω-diene epoxides: efficient access to acyclic 1,6-dicarbonyl compounds-Reference-Cited by-同舟云学术

Stereoselective tandem iridium-catalyzed alkene isomerization-cope rearrangement of ω-diene epoxides: efficient access to acyclic 1,6-dicarbonyl compounds

Published:2021 Issue:27 Volume:12 Page:9328-9332
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Suresh Rahul¹²³⁴^ORCID,Massad Itai¹²³⁴^ORCID,Marek Ilan¹²³⁴^ORCID

Affiliation:

1. Schulich Faculty of Chemistry

2. Technion – Israel Institute of Technology Technion City

3. 3200009 Haifa

4. Israel

Abstract

Iridium catalyzed alkene isomerization-cope rearrangement of ω-diene epoxide furnishes 3,4-dihydrooxepines. These oxepines are hydrolyzed to diastereomerically pure 1,6-dicarbonyl compound containing two contiguous stereocenters within acyclic system.

Funder

H2020 European Research Council

Israel Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC02575A

Reference92 articles.

1. Organic Synthesis: The Disconnection Approach , ed. S. Warren and P. Wyatt , Wiley 2008 , p. 199

2. Methods of Reactivity Umpolung