3D scaffold induces efficient bone repair: in vivo studies of ultra-structural architecture at the interface-Reference-Cited by-同舟云学术

3D scaffold induces efficient bone repair: in vivo studies of ultra-structural architecture at the interface

Published:2016 Issue:96 Volume:6 Page:93768-93776
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sagar Nitin¹²³⁴,Singh Atul Kumar⁵²³⁴,Temgire Mayur K.⁶²³⁴,Vijayalakshmi S.⁵²³⁴,Dhawan Alok⁷⁸⁹⁴,Kumar Ashutosh¹²³⁴,Chattopadhyay Naibedya¹⁰¹¹¹²⁴^ORCID,Bellare Jayesh R.¹²³⁴⁵

Affiliation:

1. Department of Biosciences and Bioengineering

2. Indian Institute of Technology-Bombay

3. Mumbai-400076

4. India

5. Centre for Research in Nanotechnology & Science

6. Department of Chemical Engineering

7. Nanomaterial Toxicology Group

8. CSIR-Indian Institute of Toxicology Research

9. Lucknow-226001

10. Division of Endocrinology and Center for Research in Anabolic Skeletal Targets in Health and Illness (ASTHI)

11. CSIR-Central Drug Research Institute

12. Lucknow-226031

Abstract

Biodegradable designer 3D scaffold bridges critical size defect and induces new bone formation as revealed by ssNMR, SEM, EDX and μ-CT in rabbit tibial model during healing. No growth factor was needed due to chemical and microstructural cues.

Funder

Department of Biotechnology , Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA20420A

Reference36 articles.

1. Restoration of mandibular continuity defects using combinations of hydroxylapatite and autogenous bone: Microscopic observations

2. Resorbable and Nonresorbable Hydroxyapatite Granules as Bone Graft Substitutes in Rabbit Cortical Defects

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