Application of lanthanide luminescence in probing enzyme activity

Abstract

Assays to monitor enzyme reactions are vital for studying enzyme mechanism, function and inhibition. We focus on recent progress in the development of enzyme activity assays using lanthanide(iii) luminescence, covering Ln(iii)-labelled biomolecules, Ln(iii) ion encapsulation within peptide sequences, reactivity-based Ln(iii) probes and discrete Ln(iii) complexes.