Stereochemical investigations of the Tetrahymena cyclase, a model system for euphane/tirucallane biosynthesis
Author:
Affiliation:
1. Department of Chemistry
2. State University of New York
3. College of Environmental Science and Forestry
4. Syracuse
5. USA
Abstract
The squalene cyclase of Tetrahymena pyriformis cyclizes 2,3-dihydrosqualene to euph-7-ene; after truncation of the substrate, “tirucall-7-enes” are formed.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB00296C
Reference18 articles.
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2. Zur Kenntnis der Triterpene. 183. Mitteilung. Über die Konstitution und Konfiguration von Tirucallol, Euphorbol und Elemadienolsäure
3. Zur Kenntnis der Triterpene. 190. Mitteilung. Eine stereochemische Interpretation der biogenetischen Isoprenregel bei den Triterpenen
4. Revisited after 50 Years: The ‘Stereochemical Interpretation of the Biogenetic Isoprene Rule for the Triterpenes’
5. Enyzmatic cyclization of 2,3-dihydrosqualene into euph-7-ene by a cell-free system from the protozoon Tetrahymena pyriformis
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