High content drug screening of primary cardiomyocytes based on microfluidics and real-time ultra-large-scale high-resolution imaging-Reference-Cited by-同舟云学术

High content drug screening of primary cardiomyocytes based on microfluidics and real-time ultra-large-scale high-resolution imaging

Published:2022 Issue: Volume: Page:
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Huang Liang¹²^ORCID,Zhang Xu³,Feng Yongxiang¹^ORCID,Liang Fei¹,Wang Wenhui¹^ORCID

Affiliation:

1. State Key Laboratory of Precision Measurement Technology and Instrument, Department of Precision Instrument, Tsinghua University, Beijing 100084, China

2. Anhui Province Key Laboratory of Measuring Theory and Precision Instrument, School of Instrument Science and Optoelectronics Engineering, Hefei University of Technology, Hefei 230009, Anhui, China

3. Beijing Institute of Collaborative Innovation, Beijing, 100094, China

Abstract

Leveraging advances in microfluidics and imaging technology, we setup a new paradigm of large-scale, high-content drug screening solutions for rapid biological processes, like cardiotoxicity.

Funder

National Natural Science Foundation of China

Thousand Young Talents Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D1LC00740H

Reference39 articles.

1. Cellular imaging in drug discovery

2. Development of a functional salivary gland tissue chip with potential for high-content drug screening