Efficient syntheses of (−)-crinine and (−)-aspidospermidine, and the formal synthesis of (−)-minfiensine by enantioselective intramolecular dearomative cyclization-Reference-Cited by-同舟云学术

Efficient syntheses of (−)-crinine and (−)-aspidospermidine, and the formal synthesis of (−)-minfiensine by enantioselective intramolecular dearomative cyclization

Published:2017 Issue:9 Volume:8 Page:6247-6256
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Du Kang¹²³⁴⁵,Yang He¹²³⁴⁵,Guo Pan¹²³⁴⁵,Feng Liang¹²³⁴⁵,Xu Guangqing¹²³⁴⁵,Zhou Qinghai⁶⁷⁸⁵⁹,Chung Lung Wa⁶⁷⁸⁵^ORCID,Tang Wenjun¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Bio-Organic & Natural Products Chemistry

2. Shanghai Institute of Organic Chemistry

3. Chinese Academy of Sciences

4. Shanghai 200032

5. China

6. Department of Chemistry

7. South University of Science and Technology of China

8. Shenzhen 518055

9. College of Chemistry

Abstract

Palladium-catalyzed enantioselective dearomative cyclization has enabled the concise and enantioselective total syntheses of (−)-crinine and (−)-aspidospermidine, as well as a formal total synthesis of (−)-minfiensine.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC01859B

Reference56 articles.

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