Diagnosis of Mycobacterium tuberculosis using palladium–platinum bimetallic nanoparticles combined with paper-based analytical devices

Author:

Tung Cheng-Yang1,Tsai Tsung-Ting2ORCID,Chiu Ping-Yeh12,Viter Roman3,Ramanavičius Arũnas4ORCID,Yu Cheng-Ju5,Chen Chien-Fu1ORCID

Affiliation:

1. Institute of Applied Mechanics, National Taiwan University, Taipei 106, Taiwan

2. Department of Orthopaedic Surgery, Bone and Joint Research Center, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan 333, Taiwan

3. Institute of Atomic Physics and Spectroscopy, University of Latvia, Jelgavas Street 3, LV-1004 Riga, Latvia

4. State Research Institute Center for Physical and Technological Sciences, Sauletekio Ave. 3, LT-10257 Vilnius, Lithuania

5. Department of Applied Physics and Chemistry, University of Taipei, Taipei 100, Taiwan

Abstract

This study demonstrates that palladium–platinum bimetallic nanoparticles (Pd@Pt NPs) can be used as the nanozyme for highly sensitive Mycobacterium tuberculosis diagnosis on a multi-layer paper-based analytical device.

Funder

National Science and Technology Council

Chang Gung Memorial Hospital, Linkou

National Taiwan University

Publisher

Royal Society of Chemistry (RSC)

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