Metabolomics reveal the protective effect of Farfarae Flos against asthma using an OVA-induced rat model

Author:

Li Jing12342,Gao Wei5673,Gao Jining893,Li Hong893,Zhang Xiang101112,Qin Xuemei123,Li Zhenyu123ORCID

Affiliation:

1. Modern Research Center for Traditional Chinese Medicine of Shanxi University

2. Taiyuan 030006

3. People's Republic of China

4. College of Chemistry and Chemical Engineering of Shanxi University

5. Department of Otolaryngology

6. Head & Neck Surgery

7. The First Hospital Affiliated with Shanxi Medical University

8. Shanxi Hospital of Integrated Traditional and Western Medicine

9. Taiyuan 030000

10. The Center for Regulatory Environmental Analytical Metabolomics

11. University of Louisville

12. USA

Abstract

A 1H NMR based metabolomics approach combined with biochemical assay and histopathological inspection has been employed to study the protective effect of PEFF against asthma on a rat model.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference45 articles.

1. Global Initiavite for Asthma, Global strategy for asthma management and prevention 2014 (2014), available from: http://www.ginasthma.org, accessed 4th December 2015

2. B7-H3 Contributes to the Development of Pathogenic Th2 Cells in a Murine Model of Asthma

3. Pathogenic memory type Th2 cells in allergic inflammation

4. T cells are the critical source of IL-4/IL-13 in a mouse model of allergic asthma

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