Doxorubicin-loaded fluorescent carbon dots with PEI passivation as a drug delivery system for cancer therapy

Author:

Hailing Yu12345ORCID,Xiufang Lv12345,Lili Wu678910,Baoqiang Li111213105ORCID,Kaichen Huang12345,Yongquan Huang12345,Qianqian Zhang12345,Chaoming Mei12345,Xiaoshuai Ren12345,Rui Zhou1415165,Hui Luo12345,Pengfei Pang12345,Hong Shan12345

Affiliation:

1. Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging

2. The Fifth Affiliated Hospital

3. Sun Yat-Sen University

4. Zhuhai

5. P. R. China

6. Key Laboratory for Photonic and Electronic Bandgap Materials

7. Ministry of Education

8. School of Physics and Electronic Engineering

9. Harbin Normal University

10. Harbin

11. Institute for Advanced Ceramics

12. State Key Laboratory of Urban Water Resource and Environment

13. Harbin Institute of Technology

14. State Key Laboratory for Mechanical Behavior of Materials

15. Xi'an Jiaotong University

16. Xi'an

Abstract

CD-PEI-mediated doxorubicin specifically targets HCC tumors, enabling real-time monitoring and therapeutic efficacy through growth inhibition and apoptosis induction.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Guangdong Province

Natural Science Foundation of Heilongjiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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