Single cell dual adherent-suspension co-culture micro-environment for studying tumor–stromal interactions with functionally selected cancer stem-like cells-Reference-Cited by-同舟云学术

Single cell dual adherent-suspension co-culture micro-environment for studying tumor–stromal interactions with functionally selected cancer stem-like cells

Published:2016 Issue:15 Volume:16 Page:2935-2945
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Chen Yu-Chih¹²³⁴⁵,Zhang Zhixiong¹²³⁴,Fouladdel Shamileh⁵³⁴,Deol Yadwinder⁵³⁴,Ingram Patrick N.⁶²⁷⁴,McDermott Sean P.⁵³⁴,Azizi Ebrahim⁵³⁴,Wicha Max S.⁵³⁴,Yoon Euisik¹²³⁴⁶

Affiliation:

1. Department of Electrical Engineering and Computer Science

2. University of Michigan

3. Ann Arbor

4. USA

5. University of Michigan Comprehensive Cancer Center

6. Department of Biomedical Engineering

7. Blvd. Ann Arbor

Abstract

An adherent-suspension cellular co-culture platform was developed for single-cell derived sphere formation and the spheres were retrieved for single-cell transcriptome analysis.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/LC/C6LC00062B

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1. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

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