Detection of HPV16 in cell lines deriving from cervical and head and neck cancer using a genosensor made with a DNA probe on a layer-by-layer matrix

Author:

Soares Juliana Coatrini12345ORCID,Melendez Matias Eliseo67849,Soares Andrey Coatrini510114ORCID,Arantes Lidia Maria Rebolho Batista6784ORCID,Rodrigues Valquiria da Cruz123412,Carvalho Andre Lopes6784,Reis Rui Manuel678413ORCID,Mattoso Luiz Henrique C.510114,Oliveira Jr Osvaldo N.1234

Affiliation:

1. Sao Carlos Institute of Physics

2. University of Sao Paulo

3. 13566-590 São Carlos

4. Brazil

5. Nanotechnology National Laboratory for Agriculture (LNNA)

6. Molecular Oncology Research Center

7. Barretos Cancer Hospital

8. 14784-400 Barretos

9. Pelé Pequeno Príncipe Research Institute

10. Embrapa Instrumentação

11. 13560-970 São Carlos

12. São Carlos School of Engineering

13. Life and Health Sciences Research Institute (ICVS)

Abstract

Electrode modified with chitosan, carbon nanotubes and a layer of cpHPV16 DNA probe to which ssHPV16 DNA binds.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Instituto Nacional de Ciência e Tecnologia em Eletrônica Orgânica

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Materials Science

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