On the feasibility of determining polymer chemical heterogeneity by SEC with continuous off-line Raman detection

Author:

Pitkänen Leena1234,Urbas Aaron A.5234,Striegel André M.1234

Affiliation:

1. Chemical Sciences Division

2. National Institute of Standards and Technology (NIST)

3. Gaithersburg

4. USA

5. Biosystems and Biomaterials Division

Abstract

Examined here is the feasibility of employing Raman spectroscopy as a detection method in size-exclusion chromatography (SEC) and related macromolecular separations, for the purposes of determining the chemical heterogeneity of copolymers.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Reference47 articles.

1. A. M. Striegel , in Multiple Detection in Size-Exclusion Chromatography, ed. A. M. Striegel, ACS Symposium Series 893, American Chemical Society, Washington, DC, 2005, pp. 2–12

2. Multiple Detection in Size-Exclusion Chromatography of Macromolecules

3. A. M. Striegel , W. W.Yau, J. J.Kirkland and D. D.Bly, Modern size-exclusion liquid chromatography, John Wiley & Sons, New Jersey, 2009, 2nd edn, p. 494

4. H. Pasch , in Multiple Detection in Size-Exclusion Chromatography, ed. A. M. Striegel, ACS Symposium Series 893, American Chemical Society, Washington, DC, 2005, pp. 230–245

5. Analysis of complex polymers by multidimensional techniques. Invited Lecture

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