Organocatalyzed [4 + 2] cycloaddition of α,β-unsaturated ketones and isatylidene malononitrile: accessing spiro[3-arylcyclohexanone]oxindole derivatives-Reference-Cited by-同舟云学术

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Organocatalyzed [4 + 2] cycloaddition of α,β-unsaturated ketones and isatylidene malononitrile: accessing spiro[3-arylcyclohexanone]oxindole derivatives

Published:2024 Issue:5 Volume:14 Page:2873-2877
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Patil Baliram R.¹²,Nichinde Chandrakant B.¹²^ORCID,Chaudhari Suryakant S.¹²,Krishna Gamidi Rama³,Kinage Anil K.¹²^ORCID

Affiliation:

1. Chemical Engineering and Process Development Division, Council of Scientific and Industrial Research-National Chemical Laboratory (CSIR-NCL), Pune 411008, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India

3. Organic Chemistry Division, Council of Scientific and Industrial Research-National Chemical Laboratory (CSIR-NCL), Pune 411008, India

Abstract

An l-proline catalyzed-Barbas-[4 + 2]-cycloaddition reaction is reported for the synthesis of spiro[3-arylcyclohexanone]oxindole derivatives. The method can tolerate a diverse substrate scope with high yields.

Funder

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D3RA07652K

Reference53 articles.

1. Tandem reactions, cascade sequences, and biomimetic strategies in total synthesis

2. Cascade Reactions in Total Synthesis

3. The art of total synthesis through cascade reactions

4. Organocatalytic cascade reactions as a new tool in total synthesis

5. Cascade polycyclizations in natural product synthesis

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