Synthesis of α-ketothioamides with elemental sulfur under solvent-free conditions in a mixer mill-Reference-Cited by-同舟云学术

Synthesis of α-ketothioamides with elemental sulfur under solvent-free conditions in a mixer mill

Published:2024 Issue:1 Volume:1 Page:38-42
ISSN:2976-8683
Container-title:RSC Mechanochemistry
language:en
Short-container-title:RSC Mechanochem.

Author:

Sahu Chandan Chittapriya¹^ORCID,Biswas Sourav¹^ORCID,Hommelsheim Renè¹^ORCID,Bolm Carsten¹^ORCID

Affiliation:

1. Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52074 Aachen, Germany

Abstract

α-Ketothioamides are formed by a mechanochemical solvent-free Willgeroth–Kindler-type reaction starting from acetophenone derivatives, amines, and elemental sulfur.

Funder

Friedrich-Ebert-Stiftung

Erasmus+

Fonds der Chemischen Industrie

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MR/D3MR00025G

Reference66 articles.

1. Analysis of US FDA-Approved Drugs Containing Sulfur Atoms

2. How do we address neglected sulfur pharmacophores in drug discovery?

3. The importance of sulfur-containing motifs in drug design and discovery

4. Prospects and Challenges in Organosulfur Chemistry

5. Organosulfur Compounds of Allium Subgenus Nectaroscordum Species

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3. Metal-free oxidative coupling of aryl acetylene with elemental sulphur and amines: facile access to α-ketothioamides;Organic & Biomolecular Chemistry;2024