High affinity rigidified AT2 receptor ligands with indane scaffolds-Reference-Cited by-同舟云学术

High affinity rigidified AT2 receptor ligands with indane scaffolds

Published:2019 Issue:12 Volume:10 Page:2146-2160
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Wallinder Charlotta¹²³⁴⁵,Sköld Christian¹²³⁴⁵,Sundholm Sara¹²³⁴⁵,Guimond Marie-Odile⁶⁷⁸⁹¹⁰,Yahiaoui Samir¹²³⁴⁵,Lindeberg Gunnar¹²³⁴⁵,Gallo-Payet Nicole⁶⁷⁸⁹¹⁰,Hallberg Mathias¹¹¹²¹³²³^ORCID,Alterman Mathias¹²³⁴⁵

Affiliation:

1. Department of Medicinal Chemistry

2. BMC

3. Uppsala University

4. SE-751 23 Uppsala

5. Sweden

6. Service of Endocrinology

7. Faculty of Medicine and Health Sciences

8. University of Sherbrooke

9. J1H 5N4 Quebec

10. Canada

11. The Beijer Laboratory

12. Department of Pharmaceutical Biosciences

13. Division of Biological Research on Drug Dependence

Abstract

Rigidification of the isobutyl side chain of drug-like AT₂ receptor agonists and antagonists that are structurally related to the first reported selective AT₂ receptor agonist 1 (C21) delivered bioactive indane derivatives.

Funder

Stiftelsen för Strategisk Forskning

Knut och Alice Wallenbergs Stiftelse

Canadian Institutes of Health Research

Vetenskapsrådet

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C9MD00402E

Reference46 articles.