Design of foldable, responsively drug-eluting polyacrylic intraocular lens bulk materials for prevention of postoperative complications-Reference-Cited by-同舟云学术

Design of foldable, responsively drug-eluting polyacrylic intraocular lens bulk materials for prevention of postoperative complications

Published:2022 Issue:41 Volume:10 Page:8398-8406
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Hong Yueze¹,Zou Haoyu¹,Hu Yulin¹,Fei Fan¹,Liang Lin¹,Liu Dong¹,Han Yuemei¹^ORCID,Lin Quankui¹^ORCID

Affiliation:

1. Department of Biomaterials, School of Ophthalmology & Optometry, Eye Hospital, Wenzhou Medical University, 270 Xueyuan Road, Wenzhou 325027, P. R. China

Abstract

An anti-proliferative drug was conjugated into bulk material via Schiff base bond to construct a pH-responsive drug-eluting IOL. The pH-responsive drug-eluting IOL can effectively prevent posterior capsular opacification after implantation.

Funder

Medical Science and Technology Project of Zhejiang Province

Science and Technology Plan Project of Wenzhou, China

Zhejiang Traditional Chinese Medicine Administration

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2022/TB/D2TB01974D

Reference48 articles.

1. Aging and Age-Related Diseases of the Ocular Lens and Vitreous Body

2. Drug-eluting intraocular lens with sustained bromfenac release for conquering posterior capsular opacification

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