Direct experimental evidence for the boronic acid-mediated bridging of DNA hybrids-Reference-Cited by-同舟云学术

Direct experimental evidence for the boronic acid-mediated bridging of DNA hybrids

Published:2023 Issue:46 Volume:59 Page:7104-7107
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Maroju Pranay Amruth¹,Thakur Anindita¹,Ganesan Ramakrishnan²^ORCID,Ray Dutta Jayati¹^ORCID

Affiliation:

1. Department of Biological Sciences, Birla Institute of Technology and Science (BITS), Pilani, Hyderabad Campus, Jawahar Nagar, Kapra Mandal, Medchal District, Hyderabad, Telangana – 500078, India

2. Department of Chemistry, Birla Institute of Technology and Science (BITS), Pilani, Hyderabad Campus, Jawahar Nagar, Kapra Mandal, Medchal District, Hyderabad, Telangana – 500078, India

Abstract

By employing terminal deoxynucleotidyl transferase (TdT), unambiguous direct mechanistic evidence for the bridging mode binding of boronic acid between two DNA duplexes via the 3′ hydroxyl moieties has been established.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC01600E

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5. Effects of free patchy ends in ssDNA and dsDNA on gold nanoparticles in a colorimetric gene sensor for Hepatitis C virus RNA