Design of an aryne-platform for the synthesis of non-racemic heterocyclic allocolchicinoids-Reference-Cited by-同舟云学术

Design of an aryne-platform for the synthesis of non-racemic heterocyclic allocolchicinoids

Published:2023 Issue:30 Volume:21 Page:6141-6150
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Gracheva Iuliia A.¹^ORCID,Schmalz Hans-Günther²^ORCID,Svirshchevskaya Elena V.¹³^ORCID,Shchegravina Ekaterina S.¹,Fedorov Alexey Yu.¹^ORCID

Affiliation:

1. Department of Organic Chemistry, National Research Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Aenue, 603950 Nizhny Novgorod, Russian Federation

2. Department of Chemistry, University of Cologne, Greinstrasse 4, 50939 Cologne, Germany

3. Laboratory of Cell Interactions, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, 16/10 Miklukho-Maklaya Street, 117997 Moscow, Russian Federation

Abstract

The first chiral allocolchicine–aryne intermediate for the diversity-oriented synthesis of heterocyclic allocolchicinoids in non-racemic form.

Funder

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00827D

Reference27 articles.

1. Update on colchicine, 2017

2. Colchicine Pharmacokinetics and Mechanism of Action

3. Therapeutic potential of colchicine in cardiovascular medicine: a pharmacological review

4. Colchicine in dermatology: Rediscovering an old drug with novel uses

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