Characterization of protein–ligand interactions by SABRE-Reference-Cited by-同舟云学术

Characterization of protein–ligand interactions by SABRE

Published:2021 Issue:39 Volume:12 Page:12950-12958
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Mandal Ratnamala¹,Pham Pierce¹^ORCID,Hilty Christian¹^ORCID

Affiliation:

1. Department of Chemistry, Texas A&M University, 3255 TAMU, College Station, TX 77843, USA

Abstract

Protein–ligand binding interactions are characterized by the para-H2 based hyperpolarization technique SABRE and flow-NMR. Binding to the protein is identified by R2 change of a ligand first interacting with the Ir polarization transfer catalyst.

Funder

Division of Chemistry

Welch Foundation

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC03404A

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