Rapamycin-based inhaled therapy for potential treatment of COPD-related inflammation: production and characterization of aerosolizable nano into micro (NiM) particles-Reference-Cited by-同舟云学术

Rapamycin-based inhaled therapy for potential treatment of COPD-related inflammation: production and characterization of aerosolizable nano into micro (NiM) particles

Published:2024 Issue:2 Volume:12 Page:387-401
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Craparo Emanuela Fabiola¹^ORCID,Cabibbo Marta¹^ORCID,Scialabba Cinzia¹,Casula Luca²^ORCID,Lai Francesco²,Cavallaro Gennara¹³^ORCID

Affiliation:

1. Laboratory of Biocompatible Polymers, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi 32, Palermo, 90123, Italy

2. Department of Life and Environmental Sciences, University of Cagliari, Via Ospedale, 72, 09124 Cagliari, Italy

3. Advanced Technology and Network Center (ATeN Center), University of Palermo, Palermo 90133, Italy

Abstract

Inhalable NiM particles made from hybrid mannosylated nanostructures are able to improve the stability of loaded rapamycin, provide controlled drug release in simulated pulmonary fluid, and actively target macrophage cells.

Funder

Ministero dell'Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2024/BM/D3BM01210G

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