Stability and toxicity of tris-tolyl bismuth(v) dicarboxylates and their biological activity towards Leishmania major-Reference-Cited by-同舟云学术

Stability and toxicity of tris-tolyl bismuth(v) dicarboxylates and their biological activity towards Leishmania major

Published:2015 Issue:41 Volume:44 Page:18215-18226
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Ong Yih Ching¹²³⁴,Blair Victoria L.¹²³⁴,Kedzierski Lukasz⁵³⁴⁶⁷,Tuck Kellie L.¹²³⁴,Andrews Philip C.¹²³⁴

Affiliation:

1. School of Chemistry

2. Monash University

3. Melbourne

4. Australia

5. Walter and Eliza Institute of Medical Research

6. Department of Medical Biology

7. University of Melbourne

Abstract

A series of tris-tolylbismuth(v) dicarboxylates, [Bi(Tol)₃(O₂CR)₂], were synthesised, characterised and evaluated againstLeishmania majorparasites demonstrating good selectivity towards promastigotes but with more moderate success against amastigotes.

Funder

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/DT/C5DT03335G

Reference28 articles.

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2. WHO, Leishmaniasis, http://www.who.int/leishmaniasis/en/

3. Antileishmanial activity of sodium stibogluconate fractions