Co-delivery of hesperetin enhanced bicalutamide induced apoptosis by exploiting mitochondrial membrane potential via polymeric nanoparticles in a PC-3 cell line
Author:
Affiliation:
1. Pharmaceutics Division
2. CSIR-Central Drug Research Institute
3. Lucknow-226031
4. India
5. Academy of Scientific & Innovative Research
6. Jawaharlal Nehru University
7. Chennai-600113
8. Pharmacokinetics and Metabolism
Abstract
In this research, we reported the co-delivery of anti-androgen drug Bicalutamide with Hesperetin in chitosan coated polycaprolactone nanoparticles to increase their therapeutic efficacy against an androgen independent prostate cancer cell lines.
Funder
Central Drug Research Institute
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA23067E
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