Sterically demanding aryl–alkyl Suzuki–Miyaura coupling

Author:

Li Chengxi123,Xiao Guolan123,Zhao Qing123,Liu Huimin456,Wang Tao456,Tang Wenjun123

Affiliation:

1. State Key Laboratory of Bio-Organic and Natural Products Chemistry

2. Shanghai Institute of Organic Chemistry

3. Shanghai 200032, P. R. China

4. AutoChem Department

5. Mettler-Toledo International Trading Co. Ltd

6. Shanghai 200233, P. R. China

Abstract

Efficient sterically demanding aryl–alkyl Suzuki–Miyaura coupling between di-ortho-substituted aryl halides and secondary alkylboronic acids has been achieved with a Pd-AntPhos catalyst.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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