Development of Lab-on-a-chip Systems for Point-of-care Applications

Abstract

The polymerase chain reaction (PCR) is a vital tool for the amplification of DNA. Microfluidics has provided an incredibly beneficial means of controlling this reaction and to optimize the entire process. This chapter introduces the PCR, describes how microfluidics has been incorporated into the PCR and reports several in-depth complete system developments (performed by one of the authors of this book). All of the principles, fabrication and detection aspects of lab-on-a-chip systems explored throughout the previous chapters are discussed.