Probing oligomerization of amyloid beta peptide in silico
Author:
Affiliation:
1. Department of Electrical and Computer Engineering
2. University of Alberta
3. Edmonton
4. Canada
5. National Research Council of Canada
Abstract
Simulations reveal molecular-level details of aggregation of amyloid β peptide that is implicated in fatal Alzheimer's disease.
Publisher
Royal Society of Chemistry (RSC)
Subject
Molecular Biology,Biotechnology
Link
http://pubs.rsc.org/en/content/articlepdf/2017/MB/C6MB00441E
Reference118 articles.
1. Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
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3. Alzheimer's Disease: The Amyloid Cascade Hypothesis
4. Prefibrillar Amyloid Aggregates Could Be Generic Toxins in Higher Organisms
5. The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
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