Establishing PQ-ERA photoclick reactions with unprecedented efficiency by engineering of the nature of the phenanthraquinone triplet state

Author:

Fu Youxin1ORCID,Alachouzos Georgios1ORCID,Simeth Nadja A.1ORCID,Di Donato Mariangela23ORCID,Hilbers Michiel F.4ORCID,Buma Wybren Jan45ORCID,Szymanski Wiktor16ORCID,Feringa Ben L.1ORCID

Affiliation:

1. Centre for Systems Chemistry, Stratingh Institute for Chemistry, Faculty for Science and Engineering, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands

2. LENS (European Laboratory for Non-Linear Spectroscopy), Via N. Carrara 1, 50019 Sesto Fiorentino (FI), Italy

3. ICCOM-CNR, Via Madonna del Piano 10, 50019 Sesto Fiorentino (FI), Italy

4. Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands

5. Institute for Molecules and Materials, FELIX Laboratory, Radboud University, Toernooiveld 7c, 6525 ED Nijmegen, The Netherlands

6. Department of Radiology, Medical Imaging Center, University of Groningen, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands

Abstract

Thiophene substitution at the 3-position of PQ enhances its reactivity in PQ-ERA photoclick reactions, resulting in increased efficiency, yields, rate constants, and oxygen tolerance, offering prospects for efficient photoclick transformations.

Funder

European Molecular Biology Organization

H2020 European Research Council

Ministerie van Onderwijs, Cultuur en Wetenschap

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Horizon 2020 Framework Programme

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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