Modelling and breaking down the biophysical barriers to drug delivery in pancreatic cancer-Reference-Cited by-同舟云学术

Modelling and breaking down the biophysical barriers to drug delivery in pancreatic cancer

Published:2024 Issue:4 Volume:24 Page:854-868
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Kpeglo Delanyo¹^ORCID,Haddrick Malcolm²,Knowles Margaret A.³,Evans Stephen D.¹^ORCID,Peyman Sally A.¹³^ORCID

Affiliation:

1. Molecular and Nanoscale Physics Group, School of Physics and Astronomy, University of Leeds, LS2 9 JT, UK

2. Medicines Discovery Catapult, Block 35, Mereside Alderley Park, Alderley Edge, SK10 4TG, UK

3. Leeds Institute of Medical Research at St James's (LIMR), School of Medicine, University of Leeds, LS2 9 JT, UK

Abstract

Developing tumour models that recapitulate the biophysical barriers that lead to drug resistance in cancer is critical in assessing new drugs and delivery mechanisms.

Funder

Engineering and Physical Sciences Research Council

Royal Society of Chemistry

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/LC/D3LC00660C

Reference62 articles.

1. Pancreatic cancer stroma: an update on therapeutic targeting strategies

2. The Current Treatment Paradigm for Pancreatic Ductal Adenocarcinoma and Barriers to Therapeutic Efficacy

3. Key biological processes driving metastatic spread of pancreatic cancer as identified by multi-omics studies

4. Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches

5. Pancreatic stellate cells: Aiding and abetting pancreatic cancer progression

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