Transition-metal-free synthesis of polysubstituted pyrrole derivatives via cyclization of methyl isocyanoacetate with aurone analogues-Reference-Cited by-同舟云学术

Transition-metal-free synthesis of polysubstituted pyrrole derivatives via cyclization of methyl isocyanoacetate with aurone analogues

Published:2018 Issue:30 Volume:16 Page:5422-5426
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wang Zhi-Peng¹²³⁴^ORCID,He Yun¹²³⁴^ORCID,Shao Pan-Lin¹²³⁴⁵^ORCID

Affiliation:

1. School of Pharmaceutical Sciences and Chongqing Key Laboratory of Natural Product Synthesis and Drug Research

2. Chongqing University

3. Chongqing 401331

4. People's Republic of China

5. College of Innovation and Entrepreneurship

Abstract

A transition-metal-free, operationally simple and atom-economic protocol that converts isocyanoacetates and aurones to 2,3,4-trisubstituted pyrroles catalyzed by NaOH was presented.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01558A

Reference57 articles.

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4. Pyrrole: Chemical Synthesis, Microwave Assisted Synthesis, Reactions and Applications: A Review

5. Acid- and metal-free synthesis of annulated pyrroles in a deep eutectic solvent

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