Reconstitution of human tissue barrier function for precision and personalized medicine

Author:

Kim Jaehoon1,Yoon Taehee12,Lee Sungryeong1ORCID,Kim Paul J.3,Kim YongTae1245ORCID

Affiliation:

1. George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA

2. Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332, USA

3. Department of Psychiatry & Behavioral Sciences, School of Medicine, Emory University, Atlanta, GA, 30322, USA

4. Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA

5. Institute for Electronics and Nanotechnology, Georgia Institute of Technology, Atlanta, GA 30332, USA

Abstract

This review highlights key design parameters for developing functional tissue barrier chips, explores recent advancements in the field, and discusses future perspectives on using these chips to realize personalized medicine.

Publisher

Royal Society of Chemistry (RSC)

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