Magnetic dummy template molecularly imprinted particles functionalized with dendritic nanoclusters for selective enrichment and determination of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in tobacco products

Author:

Zheng Yani1,Dai Yin1,Hong Junqiang2,Fan Huizhu1,Zhang Qing13,Jiang Wei4,Xu Wei1,Fei Jianwen1,Hong Junli1ORCID

Affiliation:

1. School of Pharmacy, Nanjing Medical University, Nanjing, Jiangsu 211166, China

2. Department of Radiotherapy, Fujian Medical University Affiliated Xiamen Humanity Hospital, Xiamen, Fujian 361000, China

3. Anhui Province Key Laboratory of Research & Development of Chinese Medicine, Hefei 230012, China

4. Yunnan Key Laboratory of Tobacco Chemistry, Research and Development Center of China Tobacco Yunnan Industrial Co. Ltd, Kunming, Yunnan 650231, China

Abstract

In this study, a magnetic molecularly imprinted polymer functionalized with dendritic nanoclusters was synthesized to selectively recognize NNK via the dummy template imprinting strategy, aiming to avoid residual template leakage and increase the imprinting efficiency.

Funder

Jiangsu Commission of Health

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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