Novel solid forms of oxaprozin: cocrystals and an extended release drug–drug salt of salbutamol-Reference-Cited by-同舟云学术

Novel solid forms of oxaprozin: cocrystals and an extended release drug–drug salt of salbutamol

Published:2016 Issue:41 Volume:6 Page:34110-34119
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Aitipamula Srinivasulu¹²³⁴,Wong Annie B. H.¹²³⁴,Chow Pui Shan¹²³⁴,Tan Reginald B. H.¹²³⁴⁵

Affiliation:

1. Crystallization and Particle Science

2. Institute of Chemical and Engineering Sciences

3. A*STAR (Agency for Science, Technology and Research)

4. Singapore

5. Department of Chemical & Biomolecular Engineering

Abstract

Novel solid forms of an anti-inflammatory drug, oxaprozin, were identified. A drug–drug salt of oxaprozin with salbutamol was proved promising for development of extended release tablet formulations of salbutamol.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA01802E

Reference41 articles.

1. The “High Solubility” Definition of the Current FDA Guidance on Biopharmaceutical Classification System May Be Too Strict for Acidic Drugs

2. Comparative study of oxaprozin complexation with natural and chemically-modified cyclodextrins in solution and in the solid state

3. Improvement of oxaprozin solubility and permeability by the combined use of cyclodextrin, chitosan, and bile components

4. Accessed the data from http://www.accessdata.fda.gov/scripts/cder/ob/docs/tempai.cfm

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