Fast simultaneous quantitation of valsartan and amlodipine besylate using an eco-friendly micellar HPLC-UV method: application to spiked human plasma and content uniformity testing for amlodipine

Author:

Ibrahim Fawzia A.12345,El-Brashy Amina M.12345,El-Awady Mohamed I.12345ORCID,Abdallah Nora A.12345ORCID

Affiliation:

1. Department of Pharmaceutical Analytical Chemistry

2. Faculty of Pharmacy

3. Mansoura University

4. Mansoura 35516

5. Egypt

Abstract

A simple, sensitive, and economic quantitation of two co-formulated antihypertensive drugs, valsartan and amlodipine besylate was carried out in less than 4 minutes.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference30 articles.

1. A. C. Moffat , M. D.Osselton and B.Widdop , Clarke's Analysis of Drugs and Poisons in Pharmaceuticals, Body Fluids and Postmortem Material , Pharmaceutical Press , London , 4th edn, 2011

2. A. E. Brayfield , Martindale: the Complete Drug Reference , Pharmaceutical Press , London , 2017 , http://www.medicinescomplete.com , Online version, Accessed 01.10.2017

3. Amlodipine-Valsartan Combination Decreases Central Systolic Blood Pressure More Effectively Than the Amlodipine-Atenolol Combination

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