Intramolecular through-space NMR spectroscopic effect of steric compression on 1H NMR spectroscopy

Author:

Zeng Ziyu1,Qasem Ashraf M. A.2ORCID,Blagbrough Ian S.3ORCID,Woodman Timothy J.3

Affiliation:

1. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Zhang Jiang Hi-Tech Park, Pudong, Shanghai 201203, P. R. China

2. Department of Pharmaceutical Sciences, Faculty of Pharmacy, Zarqa University, Jordan

3. Life Sciences, University of Bath, Bath BA2 7AY, UK

Abstract

This review covers the intramolecular through-space steric compression that may produce a significant deshielding effect and provides uncommon 1H NMR chemical shift confusing NMR analysts.

Funder

University of Bath

Zarqa University

Publisher

Royal Society of Chemistry (RSC)

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