Glycal approach to the synthesis of macrolide (−)-A26771B
Author:
Affiliation:
1. Medicinal and Process Chemistry Division
2. CSIR-Central Drug Research Institute (CDRI)
3. Lucknow-226031
4. India
Abstract
A convergent synthesis of macrolide natural product (−)-A26771B starting from d-glucal is reported. Key features of this synthesis involve Ferrier rearrangement, cross metathesis of chiral fragments 3 and 4 and Yamaguchi macrolactonization.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA17084A
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