Operative conversions of 3-carboxy-4-quinolones into 3-nitro-4-quinolones via ipso-nitration: potential antifilarial agents as inhibitors of Brugia malayi thymidylate kinase-Reference-Cited by-同舟云学术

Operative conversions of 3-carboxy-4-quinolones into 3-nitro-4-quinolones via ipso-nitration: potential antifilarial agents as inhibitors of Brugia malayi thymidylate kinase

Published:2015 Issue:100 Volume:5 Page:82208-82214
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Azad Chandra S.¹²³,Balaramnavar Vishal M.⁴⁵³,Khan Imran A.¹²³,Doharey Pawan K.⁶⁷²³,Saxena Jitendra K.⁶⁷²³,Saxena Anil K.¹²³

Affiliation:

1. Division of Medicinal and Process Chemistry CSIR-Central Drug Research Institute

2. Lucknow-226031

3. India

4. Global Institute of Pharmaceutical Education and Research

5. Kashipur

6. Division of Biochemistry

7. CSIR-Central Drug Research Institute

Abstract

An efficient, cost effective and green methodology for ipso nitration in the synthesis of the 3-nitro derivative of 3-carboxy 4-quinolones has been developed by the quantitative use of copper acetate and silver nitrate in water.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA18036H

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