Design, synthesis and evaluation of novel, branched trident small interfering RNA nanostructures for sequence-specific RNAi activity-Reference-Cited by-同舟云学术

Design, synthesis and evaluation of novel, branched trident small interfering RNA nanostructures for sequence-specific RNAi activity

Published:2019 Issue:59 Volume:9 Page:34166-34171
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Chandela Akash¹²³⁴,Ueno Yoshihito¹²³⁴⁵

Affiliation:

1. The United Graduate School of Agricultural Science

2. Gifu University

3. Gifu

4. Japan

5. Course of Applied Life Science

Abstract

Branched small interfering RNAs (siRNAs) are potential candidates for on-target gene silencing with enhanced serum stability. Their physical characterization also presents them as a prospective drug for systemic delivery.

Funder

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA08071F

Reference35 articles.

1. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

2. RNA-triggered gene silencing

3. RNA interference—2001

4. Revealing the world of RNA interference

5. RNA Interference and Small Interfering RNAs

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Nematicidal effects of silencing arginine kinase in the pine wood nematode, Bursaphelenchus xylophilus, determined using a dsRNA-like siRNA assembly;International Journal of Biological Macromolecules;2024-11

2. Whole-Body Physiologically-Based Pharmacokinetic Modeling of GalNAc conjugated siRNAs;2024-08-06

3. Development of nucleic acid medicines based on chemical technology;Advanced Drug Delivery Reviews;2023-08

4. Structural Modifications of siRNA Improve Its Performance In Vivo;International Journal of Molecular Sciences;2023-01-04

5. Enhanced Immunostimulatory Activity of Covalent DNA Dendrons;ChemBioChem;2021-12-23