Evaluation of binding competition and group epitopes of acetylcholinesterase inhibitors by STD NMR, Tr-NOESY, DOSY and molecular docking: an old approach but new findings-Reference-Cited by-同舟云学术

Evaluation of binding competition and group epitopes of acetylcholinesterase inhibitors by STD NMR, Tr-NOESY, DOSY and molecular docking: an old approach but new findings

Published:2015 Issue:10 Volume:6 Page:1882-1890
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Tanoli Nazish U.¹²³^ORCID,Tanoli Sheraz A. K.¹²³,Ferreira Antonio G.¹²³,Gul Sana⁴⁵⁶⁷⁸,Ul-Haq Zaheer⁴⁵⁶⁷⁸

Affiliation:

1. Laboratory of Nuclear Magnetic Resonance Federal University of Sao Carlos

2. Rodovia Washington Luiz

3. Brazil

4. Dr. Panjwani Center for Molecular Medicine and Drug Research

5. International Center for Chemicals and Biological Sciences

6. University of Karachi

7. Karachi-75210

8. Pakistan

Abstract

We suggest that the small inhibitors of AChE like coumarin and gallic acid's structure-based scaffolds may help in controlling Alzheimer's disease.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C5MD00231A

Reference39 articles.

1. Novel Stilbenes as Probes for Amyloid Plaques

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4. Molecular Modelling Approaches to the Design of Acetylcholinesterase Inhibitors: New Challenges for the Treatment of Alzheimers Disease

5. Pathways of ligand clearance in acetylcholinesterase by multiple copy sampling

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