Design, synthesis and antifungal mechanism of novel acetophenone derivatives containing 1,3,4-thiadiazole-2-thioethers-Reference-Cited by-同舟云学术

Design, synthesis and antifungal mechanism of novel acetophenone derivatives containing 1,3,4-thiadiazole-2-thioethers

Published:2022 Issue:19 Volume:46 Page:9017-9023
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Dou Li¹,Shi Huabin¹,Niu Xue¹²,Zhang Hong¹,Zhang Kankan¹^ORCID,Wu Zhibing¹^ORCID

Affiliation:

1. State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, 550025, China

2. School of Chemistry and Chemical Engineering, Guizhou University, Guiyang, 550025, China

Abstract

Key functional groups carbonyl and 1,3,4-thiadiazole-2-thiol can be obtained simultaneously in the present of sulfuric acid. Antifungal mechanism study revealed that the compound can change the permeability of the cell membrane, causing their death.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ01709A

Reference32 articles.

1. Quantification and Modeling of Crop Losses: A Review of Purposes

2. The global burden of pathogens and pests on major food crops

3. The persistent threat of emerging plant disease pandemics to global food security