Deoxygenative α-alkylation and α-arylation of 1,2-dicarbonyls-Reference-Cited by-同舟云学术

Deoxygenative α-alkylation and α-arylation of 1,2-dicarbonyls

Published:2020 Issue:34 Volume:11 Page:9101-9108
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Jin Shengfei¹²³⁴^ORCID,Dang Hang T.¹²³⁴^ORCID,Haug Graham C.¹²³⁴,Nguyen Viet D.¹²³⁴^ORCID,Arman Hadi D.¹²³⁴,Larionov Oleg V.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. The University of Texas at San Antonio

3. San Antonio

4. USA

Abstract

α-Branched carboxylic acids and other carbonyls are readily accessed by a metal- and base-free deoxygenative α-alkylation and α-arylation of 1,2-dicarbonyls via boron enolates, resulting in a tricomponent coupling with unconventional electrophiles.

Funder

National Institute of General Medical Sciences

National Science Foundation

Welch Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC03118F

Reference76 articles.

1. M. S. Singh , Reactive Intermediates in Organic Chemistry: Structure, Mechanism, and Reactions , Wiley , Hoboken , 2014