Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe-Reference-Cited by-同舟云学术

Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe

Published:2015 Issue:4 Volume:6 Page:2166-2171
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Leung Ka-Ho¹²³⁴,He Hong-Zhang¹²³⁴,He Bingyong¹²³⁴,Zhong Hai-Jing⁵⁶⁷⁸⁴,Lin Sheng¹²³⁴,Wang Yi-Tao⁵⁶⁷⁸⁴,Ma Dik-Lung¹²³⁴,Leung Chung-Hang⁵⁶⁷⁸⁴

Affiliation:

1. Department of Chemistry

2. Hong Kong Baptist University

3. Hong Kong

4. China

5. State Key Laboratory of Quality Research in Chinese Medicine

6. Institute of Chinese Medical Sciences

7. University of Macau

8. Macao

Abstract

A novel luminescent G-quadruplex-selective iridium(iii) complex was employed in a label-free G-quadruplex-based detection assay for hepatitis C virus NS3 helicase activity.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/SC/C4SC03319A

Reference80 articles.

1. DNA Helicases, Genomic Instability, and Human Genetic Disease

2. Crystal Structures of Complexes of PcrA DNA Helicase with a DNA Substrate Indicate an Inchworm Mechanism

3. Quality Control by DNA Repair

4. Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease

5. Evidence for an imino intermediate in the T4 endonuclease V reaction

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