Chitosan/PEI patch releasing EGF and the EGFR gene for the regeneration of the tympanic membrane after perforation

Author:

Lee Myung Chul1234,Seonwoo Hoon5674,Garg Pankaj8294,Jang Kyoung Je1234,Pandey Shambhavi8294,Park Sang Bae1234,Kim Hong Bae1234,Lim Jaewoon1234,Choung Yun Hoon1011124,Chung Jong Hoon12348ORCID

Affiliation:

1. Department of Biosystems & Biomaterials Science and Engineering

2. Seoul National University

3. Seoul 151-742

4. Republic of Korea

5. Department of Industrial Machinery Engineering

6. Sunchon National university

7. 315 Maegok-dong Sunchon

8. Research Institute for Agriculture and Life Sciences

9. Seoul

10. Department of Otalaryngology

11. Ajou University School of Medicine

12. Suwon 443-749

Abstract

EGF and EGFR gene-releasing PEI/chitosan patch (EErP-CPs) was developed to increase the regeneration of tympanic membrane perforations.

Funder

National Research Foundation of Korea

Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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